Except it isn't small or obscure -as a whole; it probably is for any given single diagnosis.A lot of people get worried about the small obscure stuff while ignoring threats right in their face. Worried about this kind of stuff while being 50 pounds overweight and in real danger of multiple aliments.
... But that isn't what is going to make your life hell and kill you.
I think it contributes to the weight and multiple ailments issues. Maybe not in isolation (as in lab conditions testing of single aspects for single effects) but as it is used in the real world.