- Dec 6, 2009
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Quote:
Hi Peigic - I'm not an expert on this chemical, but my understanding - which may be flawed, but is based on the information from the manufacturer (which is not available publicly as far as I know) as well as Fipronil fact sheet I linked to (I have requested the cited reference through interlibrary loan, but it will take awhile to get to me) - is that most of the chemical does stay in the skin and it does decrease through the month. This was the point of the 1/2 and 1/10th calculations toward the end. Thing is, I don't know how it partitions - is it 1 gram in the egg for every 2 grams in the skin? is it 1 gram in 10? 1 in 100? And exactly how the chemical decreases (linearly or exponentially) is another question. Usual chemical kinetics would argue for the exponential model- which is why I focused on that - but with it being in the skin, maybe it behaves differently.
-Greg
Hi Peigic - I'm not an expert on this chemical, but my understanding - which may be flawed, but is based on the information from the manufacturer (which is not available publicly as far as I know) as well as Fipronil fact sheet I linked to (I have requested the cited reference through interlibrary loan, but it will take awhile to get to me) - is that most of the chemical does stay in the skin and it does decrease through the month. This was the point of the 1/2 and 1/10th calculations toward the end. Thing is, I don't know how it partitions - is it 1 gram in the egg for every 2 grams in the skin? is it 1 gram in 10? 1 in 100? And exactly how the chemical decreases (linearly or exponentially) is another question. Usual chemical kinetics would argue for the exponential model- which is why I focused on that - but with it being in the skin, maybe it behaves differently.
-Greg